Oppenauer Oxidation is the process of conversion of secondary alcohols to ketones by selective oxidation. This reaction is named after Rupert Viktor Oppenauer. Oxidation reaction takes place in the presence of [Al(i-Pro)3] in excess of acetone.
It is an aluminium alkoxide catalysed the oxidation of a secondary alcohol to the corresponding ketone. This is reverse of the Meerwein Ponndorf Verley reduction. It is a very good method to oxidize allylic alcohols to α, β- unsaturated ketones.
In previous post we learn about Metal metal bondong in low nuclear carbonyl clusters.
Now before moving on high nuclear carbonyl cluster we should talk about isolobal analogy.
PdF-Isolobal analogy|Organometallic chemistry
In organometallic there are two type of carbonyl clusters
LNCC AND HNCC
In LNCC we can find the structure by finding metal metal bond.
DOWNLOAD PDF-Metal metal bond in LNCC
CSIR NET PREVIOUS YEAR QUESTUONS-
in last chapter we read about electrophilic aromatic substitution reaction.
now we are starting conjugate addition reaction.
An enone, also called an α,β-unsaturated carbonyl, is a type of organic compound consisting of an alkene conjugated to a ketone.
There is possibility of 1,2 or 1,4 addition which is called as michel addition.
The Michael reaction or Michael addition is the nucleophilic addition of a carbanion or another nucleophile[1][2] to an α,β-unsaturated carbonyl compound containing an electron withdrawing group. It belongs to the larger class of conjugate additions. This is one of the most useful methods for the mild formation of C–C bonds.
Whether 1,2 or 1,4-addition occurs depends on multiple variables but mostly it is determined by the nature of the nucleophile.
DOWNLOAD PDF-Conjugate addition reaction from clyden
ELECTROPHILIC AROMATIC SUBSTITUTION ELECTTOPHILIC AROMATIC SUBSTITUTION REACTION NOTESREACTION-
